Phosphorylation of Human Insulin Receptor Substrate-1 at Serine 629 Plays a Positive Role in Insulin Signaling
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چکیده
منابع مشابه
Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling.
The function of insulin receptor substrate-1 (IRS-1) is regulated by both tyrosine and serine/threonine phosphorylation. Phosphorylation of some serine/threonine residues in IRS-1 dampens insulin signaling, whereas phosphorylation of other serine/threonine residues enhances insulin signaling. Phosphorylation of human IRS-1 at Ser(629) was increased by insulin in Chinese hamster ovary cells expr...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2007
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2007-0049